Blanca Grande 515 is a hard white spring wheat. It was released by Resource Seeds, Inc in 2010. The stripe rust resistance genes Yr5 and Yr15 were introduced by four backcross generations into the susceptible cultivar Blanca Grande and then combined using marker assisted selection at UC Davis (project supported by Resource Seeds Inc.). Resource Seeds Inc. selected the best lines among BC4F2 lines homozygous for the two genes. This cultivar is very 6 similar to the original Blanca Grande but is resistant to prevalent races of the stripe rust pathogen present in California. It has medium early maturity, averages about 40 inches in plant height, and has fair straw strength. At the time of release it was resistant to stripe rust and leaf rust, moderately resistant to BYD, and susceptible to Septoria tritici leaf blotch. It subsequently became moderately susceptible to BYD and susceptible to powdery mildew. It was evaluated as Entry 1657 in the UC Regional Cereal Testing program from 2010-present for late fall planting in the Central Valley, surrounding areas, the south-central coast region, and southern desert areas of California.